[Download] "Protein Quality Control in Neurodegenerative Diseases" by Richard I. Morimoto & Yves Christen " eBook PDF Kindle ePub Free
eBook details
- Title: Protein Quality Control in Neurodegenerative Diseases
- Author : Richard I. Morimoto & Yves Christen
- Release Date : January 13, 2012
- Genre: Neuroscience,Books,Professional & Technical,Medical,Science & Nature,Life Sciences,
- Pages : * pages
- Size : 1643 KB
Description
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.